Rabbit Secondary Antibodies
ABclonal Technology APC/Cyanine7 Rabbit anti- IgM
Enables several functions including antigen binding activity identical protein binding activity and immunoglobulin receptor binding activity Acts upstream of or within several processes including early endosome to late endosome transport immunoglobulin mediated immune response and positive regulation of B cell proliferation Located in external side of plasma membrane extracellular space and perinuclear region of cytoplasm Part of B cell receptor complex and immunoglobulin complex circulating Is expressed in several structures including brain hemolymphoid system and liver Used to study non-Hodgkin lymphoma and type 1 diabetes mellitus Human ortholog(s) of this gene implicated in agammaglobulinemia Orthologous to human IGHM (immunoglobulin heavy constant mu)
ABclonal Technology PE Rabbit anti-Human Ki67 mAb
Enables protein C-terminus binding activity Involved in regulation of chromosome segregation and regulation of mitotic nuclear division Located in chromosome nuclear body and nucleolus Colocalizes with condensed chromosome Implicated in Crohn s disease breast cancer human immunodeficiency virus infectious disease and pancreatic cancer Biomarker of several diseases including Barrett s esophagus autoimmune disease of musculoskeletal system (multiple) endocrine gland cancer (multiple) gastrointestinal system cancer (multiple) and interstitial cystitis
Jackson Immuno Research Labs Alexa Fluor 488-AffiniPure Rabbit Anti-Human Serum IgA α Chain Specific
Alexa Fluor 488-AffiniPure Rabbit Anti-Human Serum IgA α Chain Specific
ABclonal Technology PE Rabbit anti-Human FGFR3 mAb
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family with its amino acid sequence being highly conserved between members and among divergent species FGFR family members differ from one another in their ligand affinities and tissue distribution A full-length representative protein would consist of an extracellular region composed of three immunoglobulin-like domains a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain The extracellular portion of the protein interacts with fibroblast growth factors setting in motion a cascade of downstream signals ultimately influencing mitogenesis and differentiation This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia
ABclonal Technology 488 Rabbit anti-Human IgE
IgE is the class of antibodies produced in the lungs skin and mucous membranes It may protect against parasite invasion but it is a major factor in allergic reactions The antigen-specific IgE interacts with mast cells and eosinophils triggers the release of histamine leukotrienes and other substances that lead to the itching sneezing and congestion of allergies - and the life threatening respiratory distress of asthma and anaphylactic shock
ABclonal Technology 647 Rabbit anti-Human IL8
The protein encoded by this gene interleukin-8 (IL-8) is a CXC chemokine and major mediator of the inflammatory response IL-8 is secreted by various cells including macrophages neutrophils and T lymphocytes and acts as a chemotactic factor guiding neutrophils to infection sites It is rapidly induced by bacterial and viral products and plays a role in systemic inflammatory response syndrome (SIRS) IL-8 contributes to bronchiolitis caused by respiratory syncytial virus (RSV) and is involved in lung inflammation in cystic fibrosis It is also linked to coronary artery disease endothelial dysfunction and promotes tumor migration angiogenesis and metastasis IL-8 binds to the CXCR2 receptor increasing blood vessel permeability Elevated IL-8 levels correlate with disease severity including sepsis This gene is part of a CXC chemokine gene cluster on chromosome 4q
ABclonal Technology 488 Rabbit anti-Human P4HB
This gene encodes the beta subunit of prolyl 4-hydroxylase a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family When present as a tetramer consisting of two alpha and two beta subunits this enzyme is involved in hydroxylation of prolyl residues in preprocollagen This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation breakage and rearrangement of disulfide bonds Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner its ability to bind thyroid hormone its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide and its function as a subunit of the microsomal triglyceride transfer protein complex
ABclonal Technology 647 Rabbit anti-Human CD72
Predicted to enable signaling receptor binding activity Predicted to be involved in cell adhesion Is integral component of plasma membrane
ABclonal Technology 647 Rabbit anti-Human CD72
Predicted to enable signaling receptor binding activity Predicted to be involved in cell adhesion Is integral component of plasma membrane
ABclonal Technology 647 Rabbit anti-Human IL-17RB
The protein encoded by this gene is a cytokine receptor This receptor specifically binds to IL17B and IL17E but does not bind to IL17 and IL17C This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation which suggested the immunoregulatory activity of this receptor
Vector Laboratories RABBIT ANTI HUMAN MFSD2A
Polyclonal Rabbit anti Human MFSD2A Antibody (FITC, N Terminus, WB)
Sino Biological Rabbit Anti-Human IgG1-Fc Secondary Antibody, Rabbit MAb
This antibody was obtained from a rabbit immunized with purified, recombinant Human IgG1-Fc.
ABclonal Technology 647 Rabbit anti-Human CD177
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration Mutations in this gene are associated with myeloproliferative diseases Over-expression of this gene has been found in patients with polycythemia rubra vera Autoantibodies against the protein may result in pulmonary transfusion reactions and it may be involved in Wegener s granulomatosis A related pseudogene which is adjacent to this gene on chromosome 19 has been identified
ABclonal Technology PE Rabbit anti-Human CD72 mAb
Predicted to enable signaling receptor binding activity Predicted to be involved in cell adhesion Is integral component of plasma membrane
ABclonal Technology 488 Rabbit anti-Human CD71
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis This receptor is required for erythropoiesis and neurologic development Multiple alternatively spliced variants have been identified